* The person should have the experience in GC and HSGC analysis for minimum 2 years.
* Independent handling of both GC and HSGC
* Calibration of GC and HSGC
* Method development by GC and HSGC
Execution of in vitro ADME studies such as met stab, hepatocyte stability, plasma protein binding, CYP in hibition assay etc.
Proficient in conducting in-vivo preclinical pharmacokinetic studies in rodents.
Execution of in-vivo tissue distribution & mass balance studies in rodents.
Responsible for caco2 assays including freezing, revival, sub-culturing, seeding and maintenance of caco2 cell lines.
Preparation of microsomes and isolation of primary hepatocytes for stability assays.
Bioanalysis of the samples from in-vivo pharmacokinetic & tissue distribution studies through LCMS/MS.
To execute the analysis of dose formulations through HPLC.
To prepare and review work procedures, protocols and SOPs for clarity, consistency, scientific correctness and applicable industry best practices.